Publications

Time-Resolved Single-Molecule FRET Reveals Length-Dependent Nucleosome Decompaction by Poly(ADP-ribose)

T Yang*, S Gopi,* L Pinet*, S Simoni, R Imhof,  D Nettels,  M Altmeyer,  R B Best, B Schuler

bioRxiv 2026.02.25.707951

https://doi.org/10.64898/2026.02.25.707951

Single-molecule FRET for probing nanoscale biomolecular dynamics

D Nettels, N Galvanetto, MT Ivanović, M Nüesch, T Yang, B Schuler

Nature Reviews Physics 6 (10), 587-605 (2024)

https://doi.org/10.1038/s42254-024-00748-7

Rapid droplet-based mixing for single-molecule spectroscopy

T Yang, KJ Buholzer, A Sottini, X Cao, A deMello, D Nettels, B Schuler

Nature Methods 20 (10), 1479-1482 (2023)

https://doi.org/10.1038/s41592-023-01995-9

Droplet-based microfluidic temperature-jump platform for the rapid assessment of biomolecular kinetics

T Yang*, A Villois*, A Kunka, F Grigolato, P Arosio, Z Prokop, A deMello, S Stavrakis

Analytical Chemistry 94 (48), 16675-16684 (2022)

https://doi.org/10.1021/acs.analchem.2c03009

Droplet-based optofluidic systems for measuring enzyme kinetics

D Hess, T Yang, S Stavrakis

Analytical and bioanalytical chemistry 412 (14), 3265-3283 (2020)

https://doi.org/10.1007/s00216-019-02294-z

A high-sensitivity, integrated absorbance and fluorescence detection scheme for probing picoliter-volume droplets in segmented flows

T Yang, S Stavrakis, A deMello

Analytical chemistry 89 (23), 12880-12887 (2017)

https://doi.org/10.1021/acs.analchem.7b03526